Spider Web, as usual, you forgot the fact they get 30%-50% of downstream sales that they did't not receive at 2016(check Q4 transcript if you think it is not true).
Firmenich(3 billion $ revenue at 2015 and still growing) payed Amyris the full costs of R&D for each molecule(10$-15$ each) and signed for 30%-50% profit share agreement.
If a company with more than 3 billion $ pays for R&D and agrees to 50% split of profit, how much profit do you think they expect? 1M$, 5M$, 10M$? those numbers are insignificant for them, if they pay for full R&D costs and agree to 50% profit share, they expect good profit from this venture.
Amyris is only starting to get the profit share for the downstream sales,those can more than double the revenue.