Thursday, March 16, 2017 11:35:33 PM
This is from November 2016 but I thought it was worth sharing.
Aegis Capital assumes coverage on Revance Therapeutics (Nasdaq: RVNC) with a Buy rating and $28 price target.
Analyst Difei Yang noted the following with today's initiation:
Opportunity to tap into a large Botulinum toxin market. Botulinum toxin is currently a $3B market, set to reach $5.6B by 2020. Though it is largely a concentrated market, with Botox holding ~85% of the market share, we believe that RT002 will stand out from primary competitors, Xeomin and Dysport, mostly because RT002 targets selective sites to limit spread to other regions and will be the first long acting toxin. We believe that RT002 can attain glabellar line market share of 21% by 2025, if on-going phase III trials is able to reproduce similar results as in the phase II BELMONT study. We estimate about $569 mil in US based revenues for FY 2025 across indications of glabellar lines, plantar fasciitis, and cervical dystonia.
Laser focus on the development of Daxibotulinumtoxin A for Injection (RT002). Management's goal of bringing an improved version of Botox to market continues to remain evident. The program is split across three indications for glabellar lines, cervical dystonia (CD), and plantar fasciitis (PF). Glabellar lines is the largest market of the three indications, and is largely dominated by Botox and dermal fillers such as Restylane and Juvederm Voluma. Within the indication for CD, RT002 is expected to compete directly with Botox and Dysport, and indirectly with oral treatments such as Anticholinergics. Lastly, RT002 is being evaluated for potential treatment of PF, a market for which injectables such a corticosteroids are the first line of treatment. Botox injections are gaining popularity, albeit off label, among podiatrists as studies are showing superiority to traditional intralesional steroid injections. RT-002 could be the first one to gain an FDA approved indication.
Upcoming catalysts. With RT002 being investigated across multiple indications, Revance has a number of potential catalytic events lined up that currently culminate in 4Q17. 1) Interim safety, efficacy, and duration results from the first two cohorts of the phase II trial in CD expected before year end 2016. 2) Top-line phase II readout from CD expected in 2017. 3) Top-line phase II readout from PF expected in 2017. 4) Top-line results from both pivotal phase III trials in glabellar lines expected in 4Q17.
Recent RVNC News
- Revance to Release First Quarter 2024 Financial Results on Thursday, May 9, 2024 • Business Wire • 05/02/2024 08:05:00 PM
- Revance to Present New DAXXIFY® Data at the American Academy of Neurology 2024 Annual Meeting • Business Wire • 04/12/2024 12:00:00 PM
- Revance Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) • Business Wire • 03/27/2024 08:05:00 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 03/08/2024 09:33:10 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 03/05/2024 10:08:05 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 03/05/2024 10:00:41 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 03/04/2024 10:34:46 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 03/04/2024 10:33:23 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 03/04/2024 09:44:22 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 03/04/2024 09:33:28 PM
- Revance Announces Pricing of $100.0 Million Public Offering of Common Stock • Business Wire • 03/04/2024 02:25:00 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 03/04/2024 11:39:11 AM
- Revance Announces Proposed Public Offering of Common Stock • Business Wire • 03/04/2024 11:37:00 AM
- Form 3 - Initial statement of beneficial ownership of securities • Edgar (US Regulatory) • 02/29/2024 09:36:29 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/28/2024 09:07:18 PM
- Revance Reports Fourth Quarter and Full Year 2023 Financial Results, Provides Corporate Update • Business Wire • 02/28/2024 09:05:00 PM
- Revance to Release Fourth Quarter and Full Year 2023 Financial Results on Wednesday February 28, 2024 • Business Wire • 02/21/2024 01:01:00 PM
- Revance to Participate in Upcoming Investor Conferences • Business Wire • 02/21/2024 01:00:00 PM
- Form SC 13G/A - Statement of acquisition of beneficial ownership by individuals: [Amend] • Edgar (US Regulatory) • 02/14/2024 08:45:13 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/13/2024 09:28:38 PM
- Form SC 13G/A - Statement of acquisition of beneficial ownership by individuals: [Amend] • Edgar (US Regulatory) • 02/13/2024 02:39:24 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/06/2024 09:04:57 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/02/2024 09:48:12 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/02/2024 09:46:53 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/02/2024 09:45:33 PM
NanoViricides Reports that the Phase I NV-387 Clinical Trial is Completed Successfully and Data Lock is Expected Soon • NNVC • May 2, 2024 10:07 AM
ILUS Files Form 10-K and Provides Shareholder Update • ILUS • May 2, 2024 8:52 AM
Avant Technologies Names New CEO Following Acquisition of Healthcare Technology and Data Integration Firm • AVAI • May 2, 2024 8:00 AM
Bantec Engaged in a Letter of Intent to Acquire a Small New Jersey Based Manufacturing Company • BANT • May 1, 2024 10:00 AM
Cannabix Technologies to Deliver Breath Logix Alcohol Screening Device to Australia • BLO • Apr 30, 2024 8:53 AM
Hydromer, Inc. Reports Preliminary Unaudited Financial Results for First Quarter 2024 • HYDI • Apr 29, 2024 9:10 AM