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Re: north40000 post# 95343

Wednesday, 03/15/2017 12:27:50 PM

Wednesday, March 15, 2017 12:27:50 PM

Post# of 97239
Amarin[AMRN]:

Rationale and design of REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial

http://investor.amarincorp.com/releasedetail.cfm?ReleaseID=1017519

http://onlinelibrary.wiley.com/doi/10.1002/clc.22692/full

Further links to dd are in my handle, and "my stocks" listed therein.

My own lipid panel. Data is from blood samples taken at my last annual physical in March 2016, and will be up-dated in March 2017. I will be 80 in April 2017.
The EPA/AA ratio is becoming widely recognized as a marker for inflammation in the CV system---my value of 1.3 is particularly good, probably better than the vast majority of the U.S. population. My doctor termed my lipid profile as "excellent," and my cardiovascular risk as "optimally suppressed."

current lipid panel marker values for me, nearly 79 years old. Off-label Vascepa since 4/1/2013.
Generic Zocor = 40 mg dose > 20 years. T1 diabetic since 1957.
HbA1c = 6.5; FBG= 111 mg/dL

Total cholesterol = 144 mg/dL
LDL-C = 70 mg/dL
TGCs = 63. "
HDL = 61. "
VLDL = 13. "

C-reactive
protein = 2.2 mg/L

APO B = 60 mg/dL;
Lp-PLA2 = 216, termed very slightly elevated;
EPA/AA Ratio = 1.3;
Omega-6/Omega-3 ratio = 1.8;
EPA = 7.0% ;
AA = 5.3%;
DHA = 2.1%;

Omega-3(EPA + DHA) Index = 9.1%, optimal > 3.2%

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