Synaptogenix Inc (SNPX)

[SF Wolf]

Neurotrope hopes to succeed with new tack in Alzheimer’s therapy
January 31, 2017

Some excerpts:

“For its Phase 2 trial of Bryostatin the company seeks to measure improvement in the Severe Impairment Battery — a neuropshycological test that measures dementia — as its primary endpoint. The SIB was chosen as the test best accepted by the industry to measure severe disease. Bryostatin, then, looks to not only reduce plaque and tau tangles, but regenerate synapses. “That’s what we hope will reverse the disease in Alzheimer’s patients,” Benison said. “Not only are we stopping the plaque and the tau, but we’re also activating these growth factors in the brain to increase the synapses.”

“When the company sought to obtain $8 million in financing it succeeded in raising triple that amount, with a total of $24.5 million raised by the final closing of its private placement, giving an indication of the type of interest Neurotrope has begun to generate.

“We’re very hopeful that the drug will give us good data in April, and that cash reserve will allow us to negotiate with pharma partners from a position of strength,”

“Our hope is,” Alkon said regarding the Alzheimer’s indication, “if we get good data, reverse and regenerative data, the FDA will say ‘Look, this is something that we can’t sit on. Let’s accelerate this.'” With fast-track status, Neurotrope would need fewer patients to get Phase 3 qualifications. “In which case, we will do a Phase 3 follow-up. We might do that with our own investor groups, we also potentially might do that in conjunction with a pharma partner. We certainly welcome a pharma partnership. There are many other indications that we think could be significantly benefited by this approach.”

https://awesomecapital.wordpress.com/2017/01/31/neurotrope-hopes-to-succeed-with-new-tack-in-alzheimers-therapy/