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Re: Jayyy post# 8788

Sunday, 02/12/2017 12:58:10 PM

Sunday, February 12, 2017 12:58:10 PM

Post# of 13735
Interesting. I definitively refuted the claim 'not one iota of peer reviewed evidence' with references and the false claim is again repeated. Here is my post for information:

You state falsely "And there's not one scrap of peer reviewed evidence that ROTH's product works"

The science says otherwise. Here is what we know about Sucanon so far in advance of the recent trial for which we are awaiting results based on publicly verifiable information on previous Sucanon studies, which the FDA referred to as "substantial clinical investigations"

Preclinical in vitro tests of Sucanon (then diab2) in rat muscle showed an up regulation of insulin receptors
Sucanon outperformed biguanides (Metformin) and sulfonylureas (Glucotrol, Micronase, Amaryl) in rat models
Pharmacokinetics showed dose response relationship, peak response 2-4 hours, no effect by 10 hours
Toxicity: none at dosing 2000x therapeutic levels in dogs and rats with therapeutic index > 10,000, no carcinogenicity, teratogenicity, or mutagenicity in mice
Clinical studies: randomized double blind placebo controlled study in 370 adult type 2 diabetics, 6 months (1 month screening, 4 months treatment, 1 month post treatment) Sucanon outperformed Glyburide in control of fasting blood sugar levels, urinary glucose excretion, and glucose tolerance testing
(All above results done under management of Bob Rieveley, Biotech holdings, before involvement of FROI or ROTH current individuals)

Finally Dr Rojas study presented at EASD annual meeting 2013 in Barcelona Spain: 97 pre diabetic adult patients (HbA1C 5.7 to 6.2) 12 weeks with normalization of HbA1C (below 5.7) in 81% of study population and decrease in weight and visceral body fat, in contrast to weight gain commonly seen with alternative medications.

For those that may not have experience in publication of scientific research or presentation at medical society meetings, papers selected for presentation are chosen through a peer review process, and the study is published in EASD's peer reviewed journal.


You go on to say "If there was positive news on the way..."

As any can read above, I never claimed positive news was on the way in the above post or otherwise. I simply post referenced information from publicly verifiable sources and have been repeatedly maligned and called names as a result