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Saturday, 02/04/2017 8:17:48 PM

Saturday, February 04, 2017 8:17:48 PM

Post# of 9136
Perjeta sc Phase I trial. The first and only trial I am aware of.

One cohort out of eight excludes rhuph20 as the excipient.

https://clinicaltrials.gov/ct2/show/NCT02738970?term=rhuph20&rank=59

Experimental: Cohort 8: SC Perjeta 1200 mg (Without rHuPH20) + SC Herceptin
Cohort 8 will include healthy male volunteers from Part 1. A single, mixed SC injection containing 1200 mg Perjeta (formulated without recombinant human hyaluronidase [rHuPH20] as an excipient) and 600 mg Herceptin will be administered.

Even the formulation for this cohort is mixed with Herceptin sc as a single injection.

This trial completes Sept. 2017


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