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Re: ash111 post# 1668

Monday, 01/30/2017 9:29:31 PM

Monday, January 30, 2017 9:29:31 PM

Post# of 6035
Thanks ash. I know you have followed many interesting biotechs.

I think the gp96 platform is very sound. It is just a matter of finding the proper combinations. Preclinically Ox40 seems to be a useful combination(ComPACT). And I am looking forward to Dr.Hutchins input as to further combinations. He headed up the preclinical work at PPHM...and they are looking at the best way to get the most out of Bavituximab. I can't help but wonder if he came to HTBX because he saw some potential synergies. Bavituximab is said to shift the tumour microenvironment to help the immune system attack the cancer. I know Dr.Hutchins led some studies where it had very good results in some combinations.

I don't know what we will hear tomorrow but the lung cancer HS-110 + nivo data could be out soon and the two year Bladder cancer HS-410 results could be out as early as August-September. And the there should be some updates on the Zika vaccine trials. These will likely be government or foundation funded...and Zika mosquito season is coming in a few months.

"The refusal of the real is the number one dogma of our time" Rene Girard

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