Thursday, January 12, 2017 5:03:18 PM
My take is they could parcel out the Melanoma combo program for non-responders. But whether the IND is picked up as well will probably be negotiable in the deal. Punit has always tried to position the company to go it alone so they always can move forward with their science. They have Australia set up as a go-it-alone option, but also expressed the desire for a "global" registration trial and the wish to partner with one of only two PD-1 drug companies that meet those requirments--Merck's Ketruda and BMS's Yervoy. Of coarse Merck would be preferred but obviously no deal yet.
I'm also curious as to how they farm out the IL-12 melanoma platform for just Melanoma, when the IL-12 + Combo platform, has potential across all indications, with even greater accuracy with TRACE. I think the Monetizing of TRACE will help calculations of ImmunnoPulse treatment cost per patient and over-all valuation of company in estimating platform/company exit opportunity valuation.
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