LadRx Corp (LADXD)

[strongbio]

The 95% may mean a few things functionally. I just remember as a trial ends and the best responders are still trucking along, every data readout their contribution to the weighted measures is greater and greater. Typically you don't wait for these people who are curative to progress you just wait long enough until statistical significance is reached. Who cares if they live 70 more years as far as the trial is concerned once it's reached. You can't continually look at the data and recalculate. It costs a ton of money. So cytr peeked at it to see if it was done maturing and was almost there. To be sure fda meeting would go well they ran numbers to calculate when all would be stat sig and it looKS like q1 2o17 gets it there. If more than 5% are super responders in some cohort, when they finally progress you can remove a lower data outlier with it and still have 95% inclusion. This shifts the curve substantially because your responders pull fewer and fewer non responders at the end of the trial. It is the final maturation wave. It might be adventageous to keep more than 95% inclusive by usually getting rid of lower points has a greater impact than adding high points to a degree of outlier saturation plateau. When the data is locked all of the super responders bear down and you really walk that low end of non responders up the inclusion chart without progression.