Avid Bioservices Inc (CDMO)

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Also: on Head+Neck Phase2, Merck already has FDA approval for Keytruda in H+N cancer.

http://www.mercknewsroom.com/news-release/prescription-medicine-news/fda-approves-mercks-keytruda-pembrolizumab-patients-recurr-0

Looks like Merck and Peregrine, through NCCN, are seeking to crank up the H+N efficacy even further through an anti-PS/anti-PD-1 immuno combination.

Success here could yield an FDA Breakthrough for the combination.

From cjgaddy info:

"#3: Ph2/Progressive Squamous Head+Neck (Bavi+Merck’s Keytruda), JOHN-HOPKINS(Sidney Kimmel CC) - PI: Ranee Mehra, MD
”Phase II Study of Pembrolizumab & Bavituximab for Progressive Recurrent/Metastatic Squamous Cell Carcinoma of the Head & Neck"
=> 9-8-16/CC/JoeShan: “The 3rd award is for a Phase II study of pembrolizumab [Merck’s Keytruda, anti-PD-1] & bavituximab in Head & Neck Cancer. We are particularly excited about this project, as it will be the first clinical trial of bavituximab with a checkpoint inhibitor. In multiple previous preclin. studies, we have observed bavituximab's potential to work synergistically with PD1 inhibitors such as pembrolizumab.”

IMO

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