Mega Millions numbers for 10/21/2016 are: 12 43 44 48 66 Mega Ball 3 Megaplier is 4 There was no Grand Prize Winner. The estimated Grand Prize was $25,000,000 ($16,600,000 cash). The next drawing is on Tuesday, October 25th, 2016 with an estimated Grand Prize of $30,000,000 ($19,900,000 cash). http://www.megamillions.com/