Tuesday, September 20, 2016 11:41:43 AM
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HCIT
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OncoSec Medical Incorporated OncoSec is pioneering new technologies to stimulate the body’s immune system to target and attack cancer. Our mission is to deliver safer and more effective cancer treatments that can provide long-term benefits for patients through our proprietary technology. OncoSec's core immunotherapy platform, ImmunoPulse, is designed to deliver DNA-based therapeutics directly into tumors and reverse the immuno-suppressive tumor microenvironment. Our lead program, ImmunoPulse IL-12, employs this intratumoral technology to enhance the local expression of interleukin-12 (IL-12). ImmunoPulse IL-12 is currently in clinical development for several indications including metastatic melanoma and triple-negative breast cancer. This includes our Phase II combination trial of ImmunoPulse IL-12 and Merck’s anti-PD-1 drug KEYTRUDA in patients with metastatic melanoma. The program’s current focus is on the significant unmet medical need in refractory and non-responders to anti-PD-1/PD-L1 therapies in melanoma. In Phase I and II clinical trials, ImmunoPulse IL-12 demonstrated a favorable safety profile and evidence of anti-tumor activity in the treatment of various solid tumors and has shown the potential to reach beyond the site of local treatment to initiate a systemic immune response. In addition to ImmunoPulse IL-12, OncoSec is also identifying and developing new immune-targeting agents for use with the ImmunoPulse platform.
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