Amarin Corp Plc (AMRN)

[Pyrrhonian]

Do you guys just dismiss this because it a) includes DHA, and b) is at a dose of 1g/d?:

OMEGA is a randomized, placebo-controlled, double-blind, multicenter trial testing the effects of omega-3-acid ethyl esters-90 (1 g/d for 1 year) on the rate of sudden cardiac death in survivors of acute myocardial infarction, if given in addition to current guideline-adjusted treatment. Secondary end points were total mortality and nonfatal clinical events. Patients (n=3851; female, 25.6%; mean age, 64.0 years) were randomized in 104 German centers 3 to 14 days after acute myocardial infarction from October 2003 until June 2007. Acute coronary angiography was performed in 93.8% and acute percutaneous coronary intervention in 77.8% of all patients.

During a follow-up of 365 days, the event rates were (omega and control groups) as follows: sudden cardiac death, 1.5% and 1.5% (P=0.84); total mortality, 4.6% and 3.7% (P=0.18); major adverse cerebrovascular and cardiovascular events, 10.4% and 8.8% (P=0.1); and revascularization in survivors, 27.6% and 29.1% (P=0.34).

http://circ.ahajournals.org/content/122/21/2152.long

It's interesting that placebo was trending better in total mortality: 4.6% (omega) vs 3.7% (placebo), with a p-value of 0.18, and MACE: 10.4% vs 8.8% (P=0.1).

Thoughts?