Innovation Pharmaceuticals Inc (IPIX)

[georgejjl]

Cellceutix is extremely proud of the Phase 2 Prurisol results. Simply put, the drug’s efficacy compares favorably with many current and various types of treatments for psoriasis (see the study linked to below), including apremilast or Otezla®, which is the leading oral FDA approved anti-psoriasis drug. It is interesting to do a side-by-side comparison between the two based on publicly available literature, and it could be argued that Prurisol performs on par with, if not better than, Otezla® at the identical stage of development

Verguo T (2016) New Therapeutic Agents for Psoriasis. M J Derma 1(1): 002.

Leo Ehrlich, Cellceutix Chief Executive Officer, commented: “Until now, Prurisol has largely been an unknown compound among many in the national psoriasis community. The completed Phase 2 study, with its compelling results, is starting to change that. We are now eager to advance Prurisol into its next FDA trial, for moderate to severe psoriasis, where we believe the drug may show even greater efficacy in treating this debilitating condition that affects millions of people. Should Prurisol go on to gain FDA approval, psoriasis sufferers, the world over, would stand to benefit greatly.”

- See more at: http://cellceutix.com/cellceutix-provides-additional-insight-into-successful-phase-2-trial-for-treating-psoriasis/#sthash.3SzK8QBE.dpuf

Numerous PIs noted patients expressed a desire to have access to Prurisol following the study’s conclusion. Moreover, the Company learned that some patients were previously unsuccessfully treated with other therapies, including biologics and apremilast (Otezla®).

- See more at: http://cellceutix.com/cellceutix-phase-2-trial-of-prurisol-for-mild-to-moderate-psoriasis-meets-primary-endpoint/#sthash.RYYjwUDy.dpuf

Of particular note, the half-life of Prurisol is shorter than that of apremilast (Otezla®) (1.3 hours vs. 6 to 9 hours). This suggests Prurisol, which acts through immunodulatory mechanisms, may not be dependent upon long-term exposure in the body to exhibit activity. A shorter half-life also may play a role in minimizing side effects commonly observed with other psoriasis treatments. The longer the drug remains in the body, the greater potential for adverse interactions with other medications and foods.

- See more at: http://cellceutix.com/cellceutix-releases-pharmacokinetics-data-from-phase-2-trial-of-prurisol-for-treating-psoriasis-data-complements-efficacy-data-reported-last-week/#sthash.FWHGDcH0.dpuf

Celgene (CELG) expects Otezla to earn revenue of up to $1 billion in 2016 and in the range of $1.5 billion–$2 billion in 2017. The company has adopted an aggressive pricing strategy to increase Otezla’s prescriptions and market share.

http://marketrealist.com/2016/05/otezla-continues-capture-market-share-psoriasis-psoriatic-arthritis-segments-2016/

Good luck and GOD bless,

George