Titan Pharmaceuticals Inc (TTNP)

[Doctor Detroit]

Opioid Dependent Mothers

Putting the pieces together, I think I can see a new patient class I was unaware of:

AN OPIATE DEPENDENT BABY IS BORN EVERY HOUR IN THE US

https://www.opiates.com/blog/opiate-dependent-baby/

Buprenorphine Treatment of Opioid-Dependent Pregnant Women: A Comprehensive Review

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506646/

Results indicate that maternal treatment with buprenorphine has comparable efficacy to methadone, although difficulties may exist with current buprenorphine induction methods. The available fetal data suggest buprenorphine results in less physiologic suppression of fetal heart rate and movements than methadone. Regarding neonatal effects, perhaps the single definitive conclusion is that prenatal buprenorphine treatment results in a clinically significant less severe neonatal abstinence syndrome (NAS) than treatment with methadone.

I think probuphine would completely solve the "difficulties" in "current buprenorphine induction methods."