Thursday, August 25, 2016 5:44:11 AM
Manikandan Raman , Benzinga Staff Writer August 19, 2016 12:28pm
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BTIG expects Geron Corporation GERN shares to be range-bound until major data release, potentially in late 2017 or 2018.
Geron's lead compound imetelstat, an inhibitor of telomerase partnered with Johnson & Johnson
JNJ's Janssen showed impressive activity in multiple hematologic malignancies including in essential thrombocythemia (ET), myelofibrosis (MF) and myelodysplastic syndrome (MDS) in pilot studies.
"We believe imetelstat has a unique potential to address the underlying cause of the hematologic malignancies, i.e. the malignant progenitor cells' clones in the bone marrow, which could differentiate it from available therapies (JAK inhibitors)," analyst Ling Wang wrote in a note.
Related Link: BTIG Sets $12 Price Target On Rockwell Medical, Sees 63% Upside
Currently, Geron, with Janssen, is executing on the ongoing Phase II IMbark trial in relapsed or refractory MF and a Phase II/III IMerge trial in chronic anemia in lower risk MDS.
In addition, positive data from the IMbark study should further boost investors' confidence in the success of a future pivotal trial.
"We project peak sales of imetelstat could reach $400+ million in the US in MF, although our projections are subject to be refined upon the finalization of the regulatory strategy," Wang highlighted.
Wang expects peak sales of imetelstat in the United States in lower risk MDS could approach $700 million in 2023.
At time of writing, shares of Geron were down 0.73 percent at $2.71.
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Recent GERN News
- Form 8-K - Current report • Edgar (US Regulatory) • 05/13/2024 08:05:15 PM
- Geron Corporation Reports First Quarter 2024 Financial Results and Business Highlights • Business Wire • 05/02/2024 11:00:00 AM
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- Geron to Participate at Upcoming Investor Conferences in April • Business Wire • 04/03/2024 08:30:00 PM
- Geron Corporation Announces Pricing of $150 Million Underwritten Offering of Common Stock and Pre-Funded Warrants • Business Wire • 03/19/2024 01:07:00 PM
- Geron Announces FDA Oncologic Drugs Advisory Committee Votes in Favor of the Clinical Benefit/Risk Profile of Imetelstat for the Treatment of Transfusion-Dependent Anemia in Patients with Lower-Risk MDS • Business Wire • 03/14/2024 07:54:00 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 02/28/2024 12:20:38 PM
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- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/16/2024 09:11:53 PM
- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/16/2024 09:10:51 PM
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- Form 4 - Statement of changes in beneficial ownership of securities • Edgar (US Regulatory) • 02/16/2024 09:08:29 PM
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- Form 8-K - Current report • Edgar (US Regulatory) • 01/30/2024 01:00:12 PM
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