Friend had skin inflammation disease, hard to diagnose. Dermatologist recommended Enbrel, said it was safe because regulated by FDA. Friend laughed in her face. That ended the relationship. She used a lot of Anatabloc (about 20 a day). Skin disease vanished. No side effect. She's still using it, but down to 10 a day to conserve what's left of a two more year supply. In addition to Anatabloc and old-fashioned doctor recommended bleach baths a couple times a week. Hard to say if it was the Anatabloc, the baths, or the combination, but the disease has been totally vanquished. Knowing what I know about anatabine I'm inclined to think that it was part of the solution to the problem.