Tuesday, June 14, 2016 1:26:37 PM
The trial—sponsored by a regional coalition of cancer centers that collaborates on clinical trials along with the National Cancer Institute and Halozyme Therapeutics—has participants in 17 cancer centers around the country. UC Irvine Health is among centers with the most patients. Its purpose is to test the side effects and dosages of a drug called PEGPH20 (or PEG20), which seems to improve the effectiveness of chemotherapy by disabling parts of a tumor’s built-in defenses.
“We still have a long road ahead,” Seery says. “In advanced cases where the cancer has spread to other organs, chemotherapy is currently the only option for treatment, and if the tumor hasn’t spread, surgery is generally the best choice. But PEG20 is a drug everyone hopes will get approved.”
http://www.ucirvinehealth.org/news/2016/05/rising-to-the-challenge/
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