Trillium Therapeutics Inc (TRIL)

[NY1972]

Expression of mouse CD47 on human cancer cells profoundly increases tumor metastasis in murine models

mCD47-expressing PC-3 cells subcutaneously implanted in NSG and CB17. Scid
mice metastasized to the sentinel lymph node, lung and liver significantly more efficiently than the control cells.
When implanted orthotopically to NOD. Scid mice, these cells spontaneously metastasized to lung and liver

http://link.springer.com/article/10.1186%2Fs12885-015-1980-8#/page-1