Results Driven Alerts

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IMNP •Azixa® and Crolibulin are two new vascular disruptive agents (VDAs) with additional anti-tumor activity demonstrated in preclinical studies. Both drugs have shown promising initial efficacy in phase I/II clinical trials in multiple solid tumors, including glioblastoma. Combination studies of VDAs with immune check-point inhibitors are underway in preclinical tumor models. These efforts will help provide the rationale for the design of a new phase II combination clinical study with a check point inhibitor.