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Sunday, 10/04/2015 7:53:06 PM

Sunday, October 04, 2015 7:53:06 PM

Post# of 80490


Chemotherapy plus PON: a new standard for Ph-positive ALL?

"Chemotherapy plus PON: a new standard for Ph-positive ALL?" an editorial by Thomas X in this week's Lancet Oncology. Editorial is a companion to the report from MD Anderson reporting 2 year event free survival of 82% in phase 2 trial. PON results superior to DAS, NIL and IMA in literature. 10 years ago median survival in Ph+ ALL was less than 1 yr.

With Incidence of Ph+ ALL in US of 2,000/yr and median survival beyond 2 yrs PON target population would be in the order of 5,000/yr in the US.

posted by mulanoom

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