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Tuesday, 08/25/2015 11:48:23 AM

Tuesday, August 25, 2015 11:48:23 AM

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Fierce biotech on Benitec http://www.fiercedrugdelivery.com/story/benitec-ipo-swoons-amid-market-rout-other-drug-delivery-focused-players-sti/2015-08-24

"The company touts its approach to RNA interference, known as DNA-directed RNAi, saying it's better than the approach to gene silencing used by Alnylam ($ALNY), Arrowhead Research ($ARWR) and others."

"Apparently, advantages of this approach include reduced toxicity and side effects because ddRNAi requires a small dosage of the DNA construct to achieve genetic change, Benitec says on its website. Late-stage trials of the hepatitis C med are expected to commence in Q2 2017. In addition, Calimmune has a license to use Benitec's ddRNAi platform on its Phase I/II candidate for HIV/AIDs."

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