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Re: cheynew post# 225280

Sunday, 07/05/2015 11:28:18 AM

Sunday, July 05, 2015 11:28:18 AM

Post# of 345704
good post cheynew and this makes me think back about a post by GJH and the possibilities of Crestor + Bavituximab and who knows, a little tweaking here and there and Bavituximab/PS Targeting just looks so promising for so many indications. A little further below that some Crestor info / AstraZeneca lawsuit info/ and the one that has me curious is "Apotex" which has a generic Crestor out as well that made its debut back in 2012. Apotex is from Canada and here we go again... why did RBC (who owns Royal Trust) sponsor a Peregrine event back in March 2014 and begin to accumulate PPHM stock ???? some puzzle pieces being left below...and RBC cetainly had a very good reason to sponsor Peregrine in March 2014 and buy PPHM shares

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...It's widely recognized that "viral Ebola replication" requires the cholesterol transporter protein NPC1.

NPCI demonstrates an affinity to bind with glycoprotein, and it's the process of cholesterol transport and GP binding that allow for viral entry, and replication.

I'm suggesting that in combination, Crestor and Bavituximab would both diminish and block these entry point pathways.

Crestor by way of diminished cholesterol transport proteins, and Bavituximab through GP differentiation by way of TIM1, TIM4 binding proteins and attachment to Phosphatidylserine.

Theoretically, Crestor and Bavituximab would overwhelm the "enveloped virulent cell", and block replication.

Or more simply put, take away the "keys" to the vehicle that the virus uses to drive.
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http://investorshub.advfn.com/boards/read_msg.aspx?message_id=107331795



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AstraZeneca Can't Shake Patent Suit Over Crestor Trials

Dec 9, 2013

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The suit, filed in August by the Medical University of South Carolina Foundation for Research Development, alleges that the drugmaker willfully ripped off the medical school's patented technology in a clinical trial to determine whether Crestor, ordinarily used to lower cholesterol, also would be effective in treating patients with vascular inflammation.

When the U.K.-based pharmaceuticals company initiated its JUPITER clinical trial, it allegedly infringed a patent owned by one of the school's professors that covers the use of a category of drugs known as statins — which includes Crestor — to treat inflammatory diseases.
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http://www.law360.com/articles/494379/astrazeneca-can-t-shake-patent-suit-over-crestor-trials



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Apotex delivers second largest generic blockbuster in Canadian history

April 2, 2012


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Apotex Inc. the largest Canadian owned pharmaceutical company, launched today Apo-Rosuvastatin, a generic version of Crestor® produced by AstraZeneca. The Apotex product is 100% Canadian made by employees and facilities dedicated to ensuring that Canada remains a global strength in generic product introduction. With annual Crestor® brand sales in Canada of over $700 million, generic Rosuvastatin represents the second largest generic product launch in this market to date. The launch of Apo-Rosuvastatin comes years before the last Crestor® patents are set to expire, in August 2020. To the Canadian healthcare system, the availability a generic rosuvastatin up to 8 years early could represent up to $3.4 billion in accumulative savings.

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http://www.apotex.com/global/about/press/20120402.asp



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Feb 25/26 RBC jumps into the picture...
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=95604270&txt2find=rbc|canada

O Cananda... O Canada... : ) and did they add atleast 100k shares?
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=95711815&txt2find=rbc|canada

PPHM's CEO King's invaluable clue in RBC presentation!
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So, no matter what one may think about the RBC presentation's level of new information, for me the mentioning of the vendor error, the usage of the 101% stat sig data reference and the fact the King sounded and looked exhausted is extremely ground breaking information for me, on top of his confident and doubtless statement that they'll enrol the 2nd ln NSCLC in 24 months OR LESS of which I have explained the consequences in this post!
http://investorshub.advfn.com/boards/read_msg.aspx?message_id=97870280&txt2find=rbc

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Yes, Royal Bank of Canada did accumulate an easy 100k shares+ so something to keep an eye on is RBC and how they all of a sudden started taking an interest in PPHM. Aug 15 we will find out how many more PPHM shares they increased their holdings by...

ROYAL BANK OF CANADA 03/31/2015 368,849 364,399 8,188.74 480

Read more: http://www.nasdaq.com/symbol/pphm/institutional-holdings#ixzz3f1vImEOi

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"Bavituximab is a first-in-class phosphatidylserine (PS)-targeting monoclonal antibody that is the cornerstone of a broad clinical
pipeline."
-- Big Pharmas nightmare... unless they are fortunate enough to have The Bavi Edge!

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