Benitec Biopharma Ltd (BNTC): "...between 20 and 220 copies of each sh...

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Benitec Biopharma Ltd (BNTC)

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Sunday, 06/28/2015 9:08:07 AM

Sunday, June 28, 2015 9:08:07 AM

"...between 20 and 220 copies of each shRNA per cell may be sufficient to abrogate replicon activity..."

"...Yet, the numbers of shRNA species required for inhibition of HCV on a per cell basis may actually be even lower than suggested by the transient replicon experiments..."

http://www.researchgate.net/profile/Sterghios_Moschos/publication/228070276_Safe_long-term_hepatic_expression_of_anti-HCV_shRNA_in_a_nonhuman_primate_model/links/004635244605c2a9e6000000.pdf

Good luck and GOD bless,

George

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