Rock Creek Pharmaceuticals Inc. (fka RCPIQ)

[Buddhahead]

Very interesting article, especially the part:

"We know from autopsies people who died cognitively intact — no dementia in their 80s — yet with brains full of plaques and tangles. You ask what protected them: They didn’t have inflammation."

"So just this year, we came to the realization that genes involved in the immune system control inflammation in the brain, and seem to be the final piece of the puzzle. First you get plaque, then tangles, then that inflammation really pushes you over the slippery slope into dementia. All this says if you have a drug cocktail where you stop amyloid, you prevent the tangles, you chill out inflammation, then you’ll stop this disease."

My comments: Tanzi said that seniors in their 80's HAD brains full of plaques and tangles but no dementia.---Missing was inflammation. But then he goes on to say you get plaques and tangles then inflammation to get dementia. Sounds to me like his comment that, like Biogen is trying to do, stop the plaque first may still have a problem if you still get inflammation.???? Or is he saying if you stop plaques, you won't get inflammation???