Saturday, May 02, 2015 8:23:47 AM
NVIV offers the best hope for SCI patients today. Treatment has consisted of 1) Decompression 2) Steroids 3) Rehab 4) Prayers. The neuroscaffold (NS) has excellent basic science evidence and a good rational for why it works. At 90 days, patient #1 progressed from AIS-A to AIS-C. Less certain is Patient #2's status.
Patient #2 apparently had injury at the T5 level. Since then, she has shown ~2/5 hip flexion (L1-L2) and ~2/5 knee extension (L3). Note that her knee extension is likely improved compared to what is documented in Jordan's 90 day exam. Most spine patients do not improve more than 2-3 spine segments below the level of injury. She has thus far shown a 10 level improvement.
Now, there have been many questions about B&B, sometimes to the extent of disrespecting the privacy of the patients. Return of B&B is VERY important for the patients, but not as important to investors. Here's why:
Pathophysiology of spinal cord injury. Recovery after immediate and delayed decompression.
(JBJS Scientific Journal)
Patient #2 had a 2 day delay in decompression. We know from animal studies that 24H delay reduces B&B return by 70%. In clinical practice, our target is MRI in 1-2 hours and decompression within 6 hours. Hence, it is rather remarkable that she has had a 10 level improvement after such delay. Return of B&B would be ~16 levels from T5 (maybe less due to autonomic innervation).
Why I invest in NVIV: I see SCI patients regularly and I would love to see this technology benefit my patients .
sy2246 Less
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