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Re: BonelessCat post# 99302

Sunday, 04/26/2015 11:59:59 PM

Sunday, April 26, 2015 11:59:59 PM

Post# of 403482
I believe ToInfinity was looking for a single entity that is effective against a broader range of gram negatives, including both CRE and P. aeruginosa. CC-1807 is very good for Klebsiella, E. coli and CRE but not P. aeruginosa. They have 6 distinct series effective against P. aeruginosa but these entities apparently aren't effective against CRE. It'd be great (as TIFB has suggested) if one compound could get both CRE, P. aeruginosa, K. pneumonia and E. coli. With the leads in the current library, it may be doable.
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