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Re: To infinity and beyond! post# 99278

Sunday, 04/26/2015 8:37:25 PM

Sunday, April 26, 2015 8:37:25 PM

Post# of 402731
To infinity- yes, Pseudomonas coverage is very important. It'd be great if CC-1807 covered Pseudomonas. It doesn't. Maybe an analogue will cover Pseudomonas. You might want to read the rest of the slide and look at some of the other compounds in Cellceutix's library. CC-1807 looks really good against E. coli, K. pneumoniae and E. cloacae, including MDR CRE strains. You don't like that? Look at the MICs for CC-1807 for ndm-1 Klebsiella compared to the big guns. You don't like that? I won't repeat the data for you.

As far as CC-1807 not being valuable or commercially viable without Pseudomonas coverage, you don't have much of an argument. Take a look at Merck's Invanz. It's broad spectrum (mostly gram negative) but doesn't cover Pseudomonas or Acinetobacter. And you can tell me about Invanz's gram positive coverage but, as you may know, it's limited. 2012 Sales for Invanz: 445 million.

Yes, and as you say, the positive data is there for all to read. Clearly, we read it differently.

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