Rock Creek Pharmaceuticals Inc. (fka RCPIQ)

[Buddhahead]

Link between proteins points to possibilities for future Alzheimer’s treatments in University of Cambridge Research, April 23, 2015

Excerpts:
"Researchers have found that the proteins that control the progression of Alzheimer’s are linked in a pathway, and that drugs targeting this pathway may be a way of treating the disease, which affects 40 million people worldwide. The findings are published today (23 April) in the journal Cell Reports."

"Earlier research looking into the link between amyloid-beta and tau had found that once the APP gets broken down, a chunk of amyloid-beta gets outside the cell, which triggers increased production of tau. “What we’re seeing is that there’s a second pathway, and that the amyloid-beta doesn’t have to be outside the cell to change levels of tau – in essence, the cell does it to itself,” said Dr Rick Livesey of the Wellcome Trust/Cancer Research UK Gurdon Institute, who led the research.

While the researchers identified this pathway in neurons with the far rarer familial form of Alzheimer’s, they found that the same pathway exists in healthy neurons as well, pointing to the possibility that targeting the same pathway in late-onset Alzheimer’s may be a way of treating the disease."

Article at:
http://www.cam.ac.uk/research/news/link-between-proteins-points-to-possibilities-for-future-alzheimers-treatments