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Saturday, 01/31/2015 12:35:37 PM

Saturday, January 31, 2015 12:35:37 PM

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Gene Seymour, on vaccines and drugs

I’ve seen the back and forth on vaccines vs drugs

Let’s look at the argument from a different perspective

Let’s only focus on influenza

We know that the influenza vaccine this year was less than 25% effective in healthy adults (and probably less in old people) and we know that TamiFlu only decreases symptoms by 1.3 days

We know that less than 50% of Americans take the flu vaccine and there are anywhere between 250K-500K people hospitalized with the flu in the US with comparable numbers in the EU

So the real issue here is human nature which is related to vaccine acceptance and compliance

Even with a universal flu vaccine that was 100% effective, compliance would certainly be less than 100%

That means there will be people who will get the flu because they were unprotected

Let’s use the lower number of 250K hospitalized

These are sick patients who consume a tremendous amount of hospitalized care which is very expensive to provide

In the UK, the average length of stay for a hospitalized patient with complicated influenza is 12 days at 2500£/day or 30,000£

By pricing a drug therapy related to the savings engendered by getting a patient out of the hospital earlier, one can assume a tremendous market world-wide (in the billions of dollars) for an effective therapy. An oral drug for out-patients is also an unmet need

In the UK, the number 10,000£ has been bandied about for a drug therapy for hospitalized patients

So, essentially, even an effective vaccine doesn’t obviate the need for an effective drug therapy, both for in and out-patients

Gene

Eugene Seymour MD MPH
Chief Executive Officer
NanoViricides, Inc
eugene@nanoviricides.com
www.nanoviricides.com
310-486-5677
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