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Thursday, 01/29/2015 5:57:35 PM

Thursday, January 29, 2015 5:57:35 PM

Post# of 30990
Telomere-lengthening procedure turns clock back years in human cells in Gizmag, By Helen Clark, January 28, 2015

Excerpts:
"Researchers at the Stanford University School of Medicine have developed a new procedure to increase the length of human telomeres. This increases the number of times cells are able to divide, essentially making the cells many years younger. This not only has useful applications for laboratory work, but may point the way to treating various age-related disorders – or even muscular dystrophy"

"Cells treated with Stanford’s procedure multiply in a similar way to much younger cells, compared with untreated cells of the same age. According to the researchers, skin cells with telomeres lengthened by the procedure were able to divide around 28 more times than untreated cells, while muscle cells divided about three more times. With this new procedure, which uses modified RNA, many more cells can be easily generated for study and drug development or disease modeling."

""Our technique is nonimmunogenic," said postdoctoral scholar John Ramunas. "Existing transient methods of extending telomeres act slowly, whereas our method acts over just a few days to reverse telomere shortening that occurs over more than a decade of normal aging. This suggests that a treatment using our method could be brief and infrequent."

Researchers are now testing the technique on other types cells and may try to treat accelerated aging disorders or target types of muscle cells in cases of Duchenne muscular dystrophy, or even heart disease."

Article at:
http://www.gizmag.com/telomere-extension-aging/35816/?utm_source=Gizmag+Subscribers&utm_campaign=333139fe1c-UA-2235360-4&utm_medium=email&utm_term=0_65b67362bd-333139fe1c-76708937

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