Galectin Therapeutics Inc. (GALT): Specifically ...... Conclusions In...

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Galectin Therapeutics Inc. (GALT)

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Re: Seagrass post# 1736

Monday, 01/05/2015 7:00:04 PM

Monday, January 05, 2015 7:00:04 PM

Specifically ......

Conclusions In experimental hyperaldosteronism, the increase in Gal-3 expression was associated with cardiac and renal fibrosis and dysfunction but was prevented by pharmacological inhibition (modified citrus pectin) or genetic disruption of Gal-3. These data suggest a key role for Gal-3 in cardiorenal remodeling and dysfunction induced by aldosterone. Gal-3 could be used as a new biotarget for specific pharmacological interventions

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