NorthWest Biotherapeutics Inc (NWBO)

[Smokey21]

When you combine this automation and cost reduction with the improvements in potency achieved by their patent issued last year, you can see how they have focused on commercializing this product from the start, and how Cognate is earning their money as our partner on the manufacturing side.

http://www.prnewswire.com/news-releases/nw-bio-receives-us-patent-on-broad-processes-for-producing-more-potent-dendritic-cells-198760831.html

This is the part I find exciting:

"NW Bio is already using these next generation methods for producing more potent dendritic cells in its production of DCVax-Direct. The same patented methods for activating dendritic cells were also used in the pre-clinical animal studies with DCVax-Direct. In those studies, injection of these potent dendritic cells into some of the tumors in each of the animals resulted in complete clearance of all tumors (both the tumors injected with DCVax-Direct and the tumors not injected) in 80-100% of the animals in the various studies, indicating a system-wide immune response.

Going forward, NW Bio's now patented methods of producing more potent dendritic cells will also enable development of the next generation of NW Bio's other two product lines: DCVax-L and DCVax-Prostate.

I would assume since we are in the middle of a controlled Phase III, switching the manufacturing technology in mid-trial is not allowed. So, as good as those results may be with the old technology, can you imagine the results with DC's that are 10X more potent? If the results we have heard of on DIRECT are any indication, I think we know the answer