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Wednesday, 11/26/2014 1:09:36 PM

Wednesday, November 26, 2014 1:09:36 PM

Post# of 158400
Love this article from today that NEWS4 found...

Regen BioPharma gets positive news on patent application
By Daily Transcript staff report
Wednesday, November 26, 2014

Article

San Diego-based Regen BioPharma Inc. (OTCBB: RGBP) has announced the receipt of a patent for treatment that attacks a gene responsible for the development of stem cell cancers.

Inventors of the intellectual property on which this patent application was filed are University of Toronto hematologist Dr. Richard Wells and Dr. Christine Ichim, a senior research consultant for Regen BioPharma.
The invention is based on findings that leukemic stem cells, which are capable of giving rise to aggressive leukemias, contained high levels of the NR2F6 gene, whereas leukemic cells that are less aggressive and cannot give rise to disease, lack this gene.

When the gene was silenced by a treatment known as shRNA , the stem cells lost leukemia forming ability and turned into normal cells. Subsequently, it was discovered that the same gene target NR2F6 is also found in malignant stem cells in other types of tumors such as breast, lung, ovarian, and colon cancers.

"Dr. Christine Ichim has spent over 10 years in identifying the importance of NR2F6 in cancer stem cells and devising means of killing these tumor-initiating cells by genetically or chemically blocking NR2F6," said David Koos, chairman and CEO of Regen BioPharma, in a statement. "We are enthusiastic about adding this new piece of intellectual property to our developmental pipeline."

Regen is a biotechnology company focused on identifying undervalued regenerative medicine applications in the stem cell field and rapidly advancing these technologies through pre-clinical and Phase 1/2 clinical trials. Currently the company is focused on developing treatments for aplastic anemia, along with gene-silencing therapies for treating cancer.
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Funny how it has taken 10 years of research to get here, and some on this board cry because of the daily gyrations of the PPS...

RGBP/BMSN

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