Amarin Corp Plc (AMRN)

[FishyFingers]

JL,

"I promise you this will be my last response to your posts..."

Thank heavens for that! Im sure I wasnt the only one getting tired of you dodging the questions and resorting to ad hominem attacks in a desperate attempt to discredit the poster.

I'll have the last word on this.

The fact remains - inflammation is NOT the cause of heart disease despite what you may believe. It is a major contributing factor but there has to be an underlying reason for persistent chronic inflammation in the first place. It does not just spontaneously manifest on a whim and then mysteriously hang around for years and decades for no reason. There is a reason adults and the elderly primarily suffer from CV disease and chronic inflammation rather than babies and teens.

This article is well worth a read:
http://www.huffingtonpost.com/dr-mark-hyman/is-your-body-burning-up-w_b_269717.html

"Everyone is treating the downstream effects of inflammation, but addressing the causes of inflammation that are upstream could help people who have multiple problems that are really linked together by this common root cause."

What was I saying about hacking at the branches?

Here's an excellent article about "What causes inflammation?" :
http://thedoctorweighsin.com/what-causes-inflammation-comprehensive-look-at-the-causes-and-effects-of-inflammation/

"Inflammation is the body’s natural response to injury. Although the symptoms of acute inflammation are unpleasant, they are necessary for the healing processes the body goes through. The characteristic symptoms are pain, redness, heat, swelling, and loss of mobility."

"When inflammation doesn’t go away, it is known as chronic or systemic inflammation, and it is no longer a pro-healing response, but rather a symptom that something has gone wrong."

"Many factors can cause a dysregulated immune response and lead to chronic inflammation. Some are genetic, and cannot be changed. More often, however, they are lifestyle factors, and completely changeable. Today, the biggest factor is weight–excess fat tissue leads to chronic inflammation.

Following weight, food is the next biggest factor, not just what we eat but what we should be eating. Smoking is a significant source of inflammation as well. After these factors, UV radiation, stress, and environmental toxins such as pesticides can be sources of inflammation as well."


"For the majority of individuals with chronic inflammation, it serves as a precursor for chronic disease, most of which are far more preventable than curable at this point. For many chronic diseases, the pathogenesis, or onset of disease, takes a long time–often at least twenty years"


"Studies have shown that chronic inflammation directly leads to a damaged endothelium, the lining of our blood vessels, and has an important but not yet fully understood role in the formation of the plaques which clog them.

While other factors, such as high blood cholesterol, are critical to the development of heart diseases as well, it now seems that inflammation is the match that starts the blaze–without an elevated level of CRP to help the formation of blood vessel clogging plaques, they would never be formed, even if all other factors were present."

EPA and AA also get a mention in the article.

So what does all this mean for Amarin and Vascepa. Well, the drug works, and it works by reducing inflammation and plaque build up. It is not going to cure anything because it doesnt remove the underlying causes of inflammation. It will, however, buy the patient more time while the geniuses of the medical community try to connect the dots. Dont hold your breath waiting for them to figure it out. Do your own research. You do not need to be a genius to figure this stuff out.