CytoSorbents Corporation (CTSO)

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Masterclass Satellite Symposium (Cytosorb ): Fix the leaky bucket to prevent fluid overload - How Cytosorb stops capillary leakage
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• Presenter: Dr. Karl Traeger, MD, PhD - Professor and Head of Cardiosurgical Intensive Care Unit, Cardiac Anaesthesia Department, University Hospital Ulm, Ulm, Germany
• Time: Friday, 28. November 2014, 14:00 pm (CEST)
• Location: Room Lijn, Hilton Antwerp

For more details: International Fluid Academy

In this Session you will learn about:
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• The overproduction of cytokines by the immune system, often called “cytokine storm”, is a hallmark of many life-threatening illnesses seen in the ICU such as severe sepsis and septic shock
• A cytokine storm can be toxic, causing direct cell death, massive capillary leakage, severe inflammation, and a cascade of events that can ultimately lead to shock and multiple organ failure
• At the heart of the Cytosorb® technology is a biocompatible, highly porous polymer designed to capture and adsorb cytokines in the ~10-50 kDa “cytokine sweet spot” where most cytokines reside
• The goal is to reduce toxic cytokine levels to prevent or mitigate organ failure and immune suppression, and to seal the capillary leak, thereby improving clinical outcome
• Key-learning issues during this lecture:
o Recognize the role of uncontrolled immune response for clinical changes of vascular tone, hemodynamic changes, capillary permeability, organ dysfunction
o Recognize the parameters of proinflammatory cytokines and the course of their activation in the context of inflammatory diseases
o Review different approaches of blood purification for modulation of cytokine levels
o Learn the effects of bead adsorber technology for cytokine removal
o Recognize different indications for hemadsorption therapy
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