Enanta Pharmaceuticals Inc (ENTA)

[willyw]

Thanks for the reply.
maybe I need to have a re-listen to the presentation again.
I listened a week ago, and it is a new type of TX, so maybe I need to re-listen or maybe not understanding correctly.

I mean it more as an SVR-4, but even that.... where does one define EOT?

per this article;

http://www.thestreet.com/story/12923612/1/regulus-gets-seat-at-hep-c-table-with-todays-impressive-drug-results.html

" Six of the 14 patients treated with RG-101 had no detectable hepatitis C virus after 29 days"

So, agreement,
but....


"Regulus said three of the six RG-101-treated patients with an RVR at one month also had no detectable virus at two months. This suggests RG-101 might have some real potency but we need to see more and longer-term data to confirm"

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(Dew wrote)
but rather 6 of 14 RVRs (viral-free patients 12 weeks after the start of treatment). Big difference!
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I'm not exactly sure that we can use the terms SVR without defining them exactly for this type of treatment.

The first day of dosing was also the last day of dosing.
So I'm unclear; exactly when does one start counting? : )

What would your thoughts be on the point where one started counting that the treatment ends for a SVR of 4, 8, 12?
I'm not sure what would constitute the EOT? (end of treatment)
On the Olysio arm it will be clear; end of dosing of a DAA.

(off to work but thank you for the correction~W)