ShinSekai...I can't tell anyone what to do with their money, but I can give you some advice as far as this stock goes. That Viopharma, now Shire trial is a phase 1b trial. As per the contract with Vipoharma there doesn't seem to be any milestone in place for a positive phase 1b trial. According to Intellects own Press Release, Orphan Drug status and a milestone payment wouldn't happen until after a positive phase 2 trial. That is many years away if/when it were to ever happen. I would say at least 5years. There isn't any good time to buy this stock IMO, not before the RS or after. This company already performed a 1 for 50 RS back in 2011. The OS was 26 million shares after that RS and is now almost at 630 MILLION! That's almost 25 times more shares! The same will be done after this RS. The heads of this company as well as the old CEO/ CSO Daniel Chain don't have any real money vested in the shares of this stock. They could care less if the stock plummets. As I have said before, if anyone is looking to redeem any of their losses here through buying this stock at lower prices then they are throwing more money away. If you are looking to spend $1000 bucks that money would be better going to a foundation for research for ALZ or whatever disease you feel fit to donate to. GLTA