Stone and Loof,
From what I understand...
Enrollment is more like a bell curve than a hockey stick. The inflection point is now with 145 sites up and running. 160 is their goal in case some centers don't enroll. It slows down when they get over 500 patients b/c they don't want more than 600 patients so it would end the bell curve.
King and Shan are visiting some of the sites. Not all but as many as they can. Most if not all of the doctors said they have never seen management visit the center. It was encouraging. They are trying to enroll as fast and as many as possible.
There are 2 look-ins next year. The first one is in the Spring and it is to see whether the safety and efficacy is good. Basically, a Go/No Go. The 2nd look-in will be Q4 2015; that will be about stop the trial(MOS and P-value) or continue on. The trial will end around Dec 2016. All of this depends on the enrollment and how quickly patients; sadly pass. So, we are 13 or 26 months away from seeing results.
Ebola was talked about a lot. The PR yesterday was worked on/submitted back in February and now it is out. Not holding my breath; but something could be brewing for Ebola. Money is there from Gates, Zuckenberg and Gov't since it is becoming a national crisis. Need to combo like with interferon or something similar.
Liver and Breast papers are coming from the doctors...Yopp and Allison Stopeck(sp) soon. In order of importance are Lung, Breast, Liver and melanoma trials. Liver could leap frog breast if results are really good. Liver is encouraging and wouldn't be surprised to see an Asian partnership for Liver cancer. Not holding my breath but seems to be the best bet at the moment.
IMO
Montana
