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Re: Beandog post# 54430

Thursday, 10/02/2014 10:07:58 AM

Thursday, October 02, 2014 10:07:58 AM

Post# of 80490
This is a post from Biomaven on the SI board:

Breakthrough designation here is significant because LDK is a very similar molecule that already received BTD and approval, which surely raises the bar some for BTD.

Indicates to me that the FDA believes (as I do) that '113 has significant advantages over LDK - likely the brain mets are the key. Perhaps also potential usage 3rd line given there was a response in a patient that had failed both LDK and crizotinib.

Peter


rum

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