Monday, September 29, 2014 7:42:00 AM
Question about AMBS's license with Dr. Urano for use of MANF.
Does AMBS still benefit if Dr. Urano uses "small molecules" to stimulate the production of the body's natural occuring "endogenous" MANF as a therapy, or is it limited to "injected" recombinant MANF?
From Dr. Urano's latest blog--"The key is to understand how MANF simulates the proliferation and enhances the function of remaining tissues. It seems like there are two independent mechanisms. There are two different mediators for MANF in our body. Thus, our goal is to develop two different types of small molecules to enhance the functions of endogenous MANF. Another option is to inject recombinant MANF. Because of several scientific reasons, we prefer small molecules at the moment."
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