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Re: None

Monday, 09/22/2014 3:56:43 PM

Monday, September 22, 2014 3:56:43 PM

Post# of 345700
Perhaps PPHM should reconsider the notion of using Bavituximab in combination with another vaccine or chemo treatment for Ebola:

http://www.newrepublic.com/article/119513/ebola-spreading-unprecedented-speed

Were earlier trials a mono-therapy?
From CJG's IBOX:

"BAVITUXIMAB ANTI-VIRAL NEWS:
I: THE 2008-2011 DTRA/TMT Gov't Contract for Anti-PS vs. Hemorrhagic Fevers http://tinyurl.com/5dxpup
TMT="Transformational Medical Technologies", TMT: www.tmti-cbdefense.org DTRA: www.dtra.mil FPDS.gov: http://tinyurl.com/4jbmkcg
3-11-11: TMT/DTRA will not extend VHF Contract - expires 3-15-11 (total revs. rec'd=$24.2mm): http://tinyurl.com/4p4hqr5
…Steve King (3-11-11 CC): "While this news is certainly disappointing, we are grateful to the TMT & DTRA for the opportunity to work together to evaluate bavituximab in this unique potential indication. We received nearly $24mm in funding over the past 33 mos… In the studies we have conducted to date under this contract, our antibodies have demonstrated a significant increase in survival in advanced preclinical models of the highly lethal Ebola virus. However in these specific studies, we weren't able to achieve an adequate dose response correlation to support advancing the program to the next stage. In no way does this dampen our enthusiasm for bavituximab and the PS-targeting platform for infectious diseases, where we believe there is still significant unrealized potential."
11-16-11: Two AntiPS posters presented at DTRA's 2011 CBD S&T/Vegas http://tinyurl.com/7pc76qd
...1) Argentine Hemorrhagic Fever/UTexas. . .2) Bacteria Infections/DSTL Porton Down/UK & Thorpe/King/C.Empig/PPHM
11-16-10: PPHM Presents AntiPS/VHFs pre-clin. data at CBDS&T BioDef Conf./Orlando http://tinyurl.com/4ve6xcl
10-2009: U-Pitt report for DARPA on Biologics Demand references Bavi http://tinyurl.com/yaefb4j
11-18-09: PPHM Presents AntiPS/VHFs pre-clin. data at DTRA/TMT Conf. http://tinyurl.com/ycrrwub
7-3-08 BioWorld Today article on PPHM's DTRA Deal: http://tinyurl.com/5kr6xk
...FULL ARCHIVE OF 2008-2011 DTRA GOV'T CONTRACT: http://tinyurl.com/6pjqt27";
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