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So they tried a different approach called "prime-boost." The first dose, to prime the immune system, was that original chimp virus-based Ebola vaccine. But for the booster two months later, they made vaccine a different way. They encased the same Ebola gene pieces inside a poxvirus that's used to make a vaccine against smallpox. (Neither vaccine type can cause Ebola.)

http://abcnews.go.com/Technology/wireStory/monkey-study-ebola-vaccine-works-booster-25329227