Rock Creek Pharmaceuticals Inc. (fka RCPIQ)

[bhp1rtp]

We know from the UC Davis study that IL-1ß causes breakdown of the gut epithelium that provides a barrier to protect the body against pathogens. Importantly, this occurs prior to the wide spread viral infection and immune cell killing

http://www.ucdmc.ucdavis.edu/publish/news/newsroom/9205

We know from Roskamp that Anatabine in a dose-dependent manner decrease in the IL-1ß response.

http://www.rfdn.org/inflammaging.html

The below article is about how a breakdown of the gut epithelium is a major cause of disease and dysfunction in modern society, accounts for at least 50% of chronic complaints, as confirmed by laboratory tests.
When the epithelium on the villi of the small intestine becomes inflamed and irritated, this allows metabolic and microbial toxins of the small intestines to flood into the blood stream. This event compromises the liver, the lymphatic system, and the immune response including the endocrine system.
Some of the most incurable diseases are caused by this exact mechanism, where the body attacks its own tissues.
This is commonly called auto-immune disease.

It is often the primary cause of the following common conditions: asthma, food allergies, chronic sinusitis, eczema, urticaria, migraine, irritable bowel, fungal disorders, fibromyalgia, and inflammatory joint disorders including rheumatoid arthritis are just a few of the diseases that can originate with leaky gut. It also contributes to PMS, uterine fibroid, and breast fibroid.
Leaky Gut Syndrome is often the real basis for chronic fatigue syndrome and pediatric immune deficiencies.
Leaky Gut Syndrome is reaching epidemic proportions within the population.

http://www.functionalmedicineuniversity.com/public/Leaky-Gut.cfm