New Disease Pathway Identified for ALS (NF-kB involved) this is the first time its partner in crime – a protein known as nuclear factor- kappa B (NF-kB) – has been tied to ALS. NF-kB is a key regulator for the synthesis of a number of factors associated with innate immunity and inflammationhttp://www.alscenter.org/news/rss_from_the_packard_center/11_11_15.html Harmful action of NF-kB is inhibited by the anatabine in Anatabloc.