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Re: Whalatane post# 31200

Sunday, 07/27/2014 12:09:45 PM

Sunday, July 27, 2014 12:09:45 PM

Post# of 424038
Thanks Kiwi for reminding us of the important relationship between elapsed time and EPA impact in JELIS. Your statement("it took about 2 years to really see the divergence of event lines")is true to a point, but a bit misleading when you view the full cumulative incidence timeline of major events in JELIS. When I look at that cumulative graph in Matsuzaki (Circulation Journal, July 2009)the three year point stands out as the distinct trial duration mark for separation of control vs EPA group outcomes. Overlaying this reality on Reduce-It suggests that JL's enthusiastic hopes(see #31195)for significant data as early as mid-2013 is overly optimistic by a year. Wish it weren't so. Perhaps our best hope for quick Truth is if FDA looks at quarterly DMC data reports for early signs that egg may be accumulating on FDA's face--but it isn't clear to me if FDA can even access this data--anybody know?
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