Friday, July 25, 2014 10:44:53 AM
NORCROSS, Ga., July 25, 2014 (GLOBE NEWSWIRE) -- Galectin Therapeutics (Nasdaq:GALT), the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, announced the Company will hold a webcast on Tuesday, July 29, 2014 at 8:30 a.m. Eastern Daylight Time to discuss the findings from cohort 2 of a Phase 1 clinical trial evaluating its galectin inhibitor GR-MD-02 in fatty liver disease (NASH) with advanced fibrosis.
Registration and access to the live webcast can be found at the following link: http://w.on24.com/r.htm?e=824339&s=1&k=03EDE683D3FB138088B03D9226655B4B Audio only can be accessed using the following call-in number: (866) 219-3563, conference ID: 74783858. Peter G. Traber, M.D., Chief Executive Officer, President and Chief Medical Officer of Galectin Therapeutics Inc., will present the findings of cohort 2. A corresponding presentation will be posted on the Company website (www.galectintherapeutics.com) prior to the presentation.
The first-in-man study, which enrolled eight patients in the second cohort, is evaluating the safety, tolerability, and exploratory biomarkers for efficacy for single and multiple doses of galectin-inhibiting drug GR-MD-02 when administered to patients with fatty liver disease (NASH) with advanced fibrosis. Patients in cohort 2 were dosed at 4 mg/kg, which is double the dose given in cohort 1. The trial used FibroScan(R) to gain experience in the potential use of this device for future Phase 2 studies. FibroScan(R) is approved by the U.S. Food and Drug Administration for noninvasive measurement of shear wave speed at 50 Hz in the liver and may be used as an aid to clinical management of patients with liver disease.
The Phase 1 multi-center, blinded (to healthcare providers and patients) clinical trial is being conducted in patients with NASH with advanced fibrosis (Brunt Stage 3) who receive four doses of GR--MD--02 over a 42--day period. Each of the three planned cohorts consists of eight patients, six randomized to receive active drug and two randomized to receive placebo. Trial design details can be found at http://clinicaltrials.gov/ct2/show/NCT01899859?term=gt-020&rank=1.
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