NanoViricides Inc. (NNVC)

[bloomvest]

Blood Brain Barrier issue is going to add years to tox. Thats a fact.
Passing the BBB may be an excellent attribute , but the fact is this will add significantly to tox studies. I cant believe any country in the world will allow a human study without a complete tox study.

Trade this POS. It's the only way to make money with NNVC.

http://en.wikipedia.org/wiki/Blood%E2%80%93brain_barrier

Nanoparticles
Nanotechnology may also help in the transfer of drugs across the BBB.[12][13] Recently, researchers have been trying to build liposomes loaded with nanoparticles to gain access through the BBB. More research is needed to determine which strategies will be most effective and how they can be improved for patients with brain tumors. The potential for using BBB opening to target specific agents to brain tumors has just begun to be explored.

Delivering drugs across the blood–brain barrier is one of the most promising applications of nanotechnology in clinical neuroscience. Nanoparticles could potentially carry out multiple tasks in a predefined sequence, which is very important in the delivery of drugs across the blood–brain barrier.

A significant amount of research in this area has been spent exploring methods of nanoparticle-mediated delivery of antineoplastic drugs to tumors in the central nervous system. For example, radiolabeled polyethylene glycol coated hexadecylcyanoacrylate nanospheres targeted and accumulated in a rat gliosarcoma.[14] However, this method is not yet ready for clinical trials, due to the accumulation of the nanospheres in surrounding healthy tissue.

It should be noted that vascular endothelial cells and associated pericytes are often abnormal in tumors and that the blood–brain barrier may not always be intact in brain tumors. Also, the basement membrane is sometimes incomplete. Other factors, such as astrocytes, may contribute to the resistance of brain tumors to therapy.[15][16]