Benitec Biopharma Ltd (BNTC): Following review of data from the first...

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Benitec Biopharma Ltd (BNTC)

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Re: RCH68 post# 956

Sunday, 07/20/2014 11:03:07 PM

Sunday, July 20, 2014 11:03:07 PM

Following review of data from the first patient treated with TT-034 on 29 May 2014, the independent DSMB has recommended that the study can continue without modification.

The first patient dosed in the trial has to date experienced no treatment-related adverse effects. Liver biopsy results from the first patient were encouraging and in line with expectations. TT-034 DNA and short hairpin RNA (shRNA) were both detected in the biopsy at sub-therapeutic levels, indicating that liver *transduction occurred.

*Transduction

.

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