Avid Bioservices Inc (CDMO)

[biopharm]

I'm not sure if that "Cancer Therapeutics Lab" was owned by Peregrine...but Alan Epstein was certainly associated with that lab.

http://www.sbir.gov/sbirsearch/detail/116872

http://www.biocentury.com/companies/cancer_therapeutics_laboratories_inc

http://sbirsource.com/sbir/firms/15515-cancer-therapeutics-laboratories-inc

-----------------------------------------------

published July 2010

http://www.jimmunol.org/content/early/2010/07/19/jimmunol.1000901.full.pdf

-----------------------------------------------

Oct 15, 2014

At the present time, Dr. Epstein is investigating the role of human suppressor cell populations such as T-regulatory cells (Treg) and myeloid derived suppressor cells (MDSC) on tumor growth and immune escape. Antibodies directed against these cells are being generated and conjugated to co-stimulatory molecules or siRNA reagents capable of silencing key genes associated with suppressor cell function. The major direction of the laboratory is to develop novel methods of treating suppressor cells to enable tumor and dendritic cell vaccines to provide an effective and lasting immune response to tumors. As in vivo models, several syngeneic murine tumor models are being used to test the effectiveness of these approaches before specific reagents are translated to man.

http://www.lungcancerfoundation.org/2013/10/o-c-t-1-5-a-l-a-n-l-e-p-s-t-e-i-n-m-d-p-h-d/